The colposcope, an instrument used to see a magnified view of the cervix, was invented in 1925.
A LEEP procedure using a heated loop of platinum to excise a patch of cervical tissue was developed by Aurel Babes in 1927.
The Pap smear was developed by Georgios Papanikolaou in 1928.
Diethylstilbestrol, used from 1938 to 1971 to prevent preterm labour and miscarriage, is also strongly associated with the development of cervical stenosis and other abnormalities in the daughters of the exposed women.
Diethylstilbestrol, used from 1938 to 1971 to prevent preterm labour and miscarriage, is also strongly associated with the development of cervical stenosis and other abnormalities in the daughters of the exposed women.
They also thicken cervical mucus and thin the lining of the uterus, enhancing their effectiveness. ==Clinical significance== ===Cancer=== In 2008, cervical cancer was the third-most common cancer in women worldwide, with rates varying geographically from less than one to more than 50 cases per 100,000 women.
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