When taken by mouth, effects begin in 30 to 45 minutes and last 3 to 6 hours. MDMA was first developed in 1912 by Merck.
It was used to enhance psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s.
It was used to enhance psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s.
The average content of MDMA in a preparation is 70 to 120 mg with the purity having increased since the 1990s. MDMA is usually consumed by mouth.
In 2016, about 21 million people between the ages of 15 and 64 used ecstasy (0.3% of the world population).
In the United States, as of 2017, about 7% of people have used MDMA at some point in their lives and 0.9% have used it in the last year. Short-term adverse effects include grinding of the teeth, blurred vision, sweating and a rapid heartbeat, and extended use can also lead to addiction, memory problems, paranoia and difficulty sleeping.
In 2017 the United States Food and Drug Administration (FDA) approved limited research on MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD), with some preliminary evidence that MDMA may facilitate psychotherapy efficacy for PTSD. ===Other=== Small doses of MDMA are used by some religious practitioners as an entheogen to enhance prayer or meditation.
It belongs to the substituted amphetamine classes of drugs and has stimulant and hallucinogenic effects. MDMA is illegal in most countries and, as of 2018, has no approved medical uses. ==Effects== In general, MDMA users report feeling the onset of subjective effects within 30 to 60 minutes of oral consumption and reaching peak effect at 75 to 120 minutes, which then plateaus for about 3.5 hours.
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